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Quorum sensing inhibition through site-directed mutation by deletion PCR.

Biochemical and biophysical research communications - 11 Jun 2023

Jeong Yechan, Moon Sunwoo, Shin Jae-Hwa

Abstract excerpt

Quorum sensing induces biofilms and virulence factors that are adverse industrially and medically. Nowadays, quorum sensing inhibitions focus on signal analogs or signal degradation, but these methods have several downsides, which are temporal and affected by several environmental factors. In this research, we used deletion PCR to perform site-directed mutagenesis on the quorum sensing pathway gene and then...

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PMID: 37060827
DOI: 10.1016/j.bbrc.2023.03.078

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