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Article

Repression of HNF1α-mediated transcription by amino-terminal enhancer of split (AES).

Biochemical and biophysical research communications - 1 Jan 2000

Han Eun Hee, Gorman Amanda A, Singh Puja, Chi Young-In

Abstract excerpt

HNF1α (Hepatocyte Nuclear Factor 1α) is one of the master regulators in pancreatic beta-cell development and function, and the mutations in Hnf1α are the most common monogenic causes of diabetes mellitus. As a member of the POU transcription factor family, HNF1α exerts its gene regulatory function through various molecular interactions; however, there is a paucity of knowledge in their functional complex...

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Identifiers

PMID: 26549228
DOI: 10.1016/j.bbrc.2015.11.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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