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Article

Background differences in baseline and stimulated MMP levels influence abdominal aortic aneurysm susceptibility.

Atherosclerosis - 1 Dec 2015

Dale Matthew A, Suh Melissa K, Zhao Shijia, Meisinger Trevor, Gu Linxia, Swier Vicki J, Agrawal Devendra K, Greiner Timothy C, Carson Jeffrey S, Baxter B Timothy, Xiong Wanfen

Abstract excerpt

OBJECTIVE: Evidence has demonstrated profound influence of genetic background on cardiovascular phenotypes. Murine models in Marfan syndrome (MFS) have shown that genetic background-related variations affect thoracic aortic aneurysm formation, rupture, and lifespan of mice. MFS mice with C57Bl/6 genetic background are less susceptible to aneurysm formation compared to the 129/SvEv genetic background. In this...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26546710
DOI: 10.1016/j.atherosclerosis.2015.10.006
PMCID: PMC4683999

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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