Article
Association of TRPM Channel Gene Polymorphisms with Systemic Sclerosis.
In vivo (Athens, Greece) - 1 Jan 2000
Oztuzcu Serdar, Onat Ahmet M, Pehlivan Yavuz, Alibaz-Oner Fatma, Donmez Salim, Cetin Gozde Y, Yolbas Servet, Bozgeyik Ibrahim, Yilmaz Neslihan, Ozgen Metin, Cagatay Yonca, Kisacik Bunyamin, Koca Suleyman S, Pamuk Omer Nuri, Sayarlioglu Mehmet, Direskeneli Haner, Demiryurek Abdullah T
Abstract excerpt
BACKGROUND/AIM: Systemic sclerosis (SSc) is an inflammatory disease characterized by vascular abnormalities and fibrosis. The aim of the present study was to investigate the possible role of transient receptor potential melastatin (TRPM) channel genes in the susceptibility and phenotype expression of SSc. MATERIALS AND METHODS: A total of 339 patients with SSc and 302 healthy controls were studied. Genomic DNA...
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