Article
TRPC6 gene variants and neuropsychiatric lupus.
Journal of neuroimmunology - 15 Nov 2015
Ramirez Giuseppe A, Lanzani Chiara, Bozzolo Enrica P, Citterio Lorena, Zagato Laura, Casamassima Nunzia, Canti Valentina, Sabbadini Maria Grazia, Rovere-Querini Patrizia, Manunta Paolo, Manfredi Angelo A
Abstract excerpt
Neuropsychiatric manifestations of systemic lupus erythematosus (NPSLE) influence patients' quality of life and their survival. Little is known about the pathophysiological bases of NPSLE and accordingly there are no specific therapeutic agents to be employed in this setting. Genetic research in systemic lupus erythematosus (SLE) is rapidly evolving as a tool to find clues about the pathogenic determinants of the...
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