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Article

Identification of candidate loci at 6p21 and 21q22 in a genome-wide association study of cardiac manifestations of neonatal lupus.

Arthritis and rheumatism - 1 Nov 2010

Clancy Robert M, Marion Miranda C, Kaufman Kenneth M, Ramos Paula S, Adler Adam, Harley John B, Langefeld Carl D, Buyon Jill P

Abstract excerpt

OBJECTIVE: Cardiac manifestations of neonatal lupus, comprising atrioventricular conduction defects and cardiomyopathy, occur in fetuses exposed to anti-Ro/SSA antibodies, and carry substantial mortality. There is strong evidence of a genetic contribution to the risk. This study was undertaken to evaluate single-nucleotide polymorphisms (SNPs) for associations with cardiac neonatal lupus. METHODS: Children of...

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Identifiers

PMID: 20662065
DOI: 10.1002/art.27658
PMCID: PMC3593718

Genes

BTNL2
MICB
NOTCH4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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