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Article

Standardization, Evaluation, and Area-Under-Curve Analysis of Human and Murine Treg Suppressive Function.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2016

Akimova Tatiana, Levine Matthew H, Beier Ulf H, Hancock Wayne W

Abstract excerpt

FOXP3+ T-regulatory (Treg) cells have important roles in immune homeostasis, and alterations in their number and function can predispose to diseases ranging from autoimmunity to allograft rejection and tumor growth. Reliable identification of human Tregs remains a persistent problem due to a lack of specific markers. The most definitive Treg characterization currently involves combined assessment of phenotypic,...

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Identifiers

PMID: 26530794
DOI: 10.1007/978-1-4939-3139-2_4
PMCID: PMC5554116

Genes

FOXP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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