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Article

Neuregulin 3 and its roles in schizophrenia risk and presentation.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Mar 2018

Avramopoulos Dimitrios

Abstract excerpt

Neuregulins, a four-member family of epidermal growth factor-like signaling molecules, have been studied for over two decades. They were first implicated in schizophrenia in 2002 with the detection of linkage and association at the NRG1 locus followed after a few years by NRG3. However, the associations with disease have not been very consistently observed. In contrast, association of NGR3 variants with disease...

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Identifiers

PMID: 28556469
DOI: 10.1002/ajmg.b.32552
PMCID: PMC5735014

Genes

NRG3
NRG1

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