Article
Interleukin-6 promoter haplotypes are associated with etanercept response in patients with rheumatoid arthritis.
Clinical rheumatology - 1 Dec 2015
Schotte Heiko, Schmidt Hartmut, Gaubitz Markus, Drynda Susanne, Kekow Jörn, Willeke Peter, Schlüter Bernhard
Abstract excerpt
Indices prognosticating anti-tumor necrosis factor (TNF) response in patients with rheumatoid arthritis are a matter of interest. Differential outcome under anti-TNF and anti-interleukin-6 (IL-6) therapy raises the question whether genetic polymorphisms that have previously been linked to IL-6 production are associated with response to anti-TNF therapy. Fifty (50) rheumatoid arthritis (RA) patients were treated...
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