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Article

Deregulation of miR-1, miR486, and let-7a in cytogenetically normal acute myeloid leukemia: association with NPM1 and FLT3 mutation and clinical characteristics.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Apr 2016

Seyyedi Samaneh Sadat, Soleimani Masoud, Yaghmaie Marjan, Ajami Monireh, Ajami Mansoureh, Pourbeyranvand Shahram, Alimoghaddam Kamran, Akrami Seyed Mohammad

Abstract excerpt

Cytogenetically normal acute myeloid leukemia (CN-AML) constitutes the largest subgroup of AML patients that is associated with molecular alteration. MiRNAs have been shown to be aberrantly expressed in CN-AML. In addition, specific miRNA (miR) expression patterns were found to be associated with certain genetic alterations in these patients. This study investigated the expression level of miR-1, miR-486, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26526573
DOI: 10.1007/s13277-015-4289-y

Genes

NPM1
FLT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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