Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Haemophilus influenzae LicB contributes to lung damage in an aged mice co-infection model.

Microbial pathogenesis - 1 Jan 2016

Bondy Jessica, Osharovich Sofya, Storm Julie, Durning Graham, McAuliffe Timothy, Fan Xin

Abstract excerpt

Phosphorylcholine (ChoP) decoration of lipopolysaccharides is an important virulence strategy adopted by Haemophilus influenzae to establish a niche on the mucosal surface and to promote adherence to the host cells. The incorporation of ChoP on the LPS surface involves the lic1 operon, which consists of the licA, licB, licC, and licD genes. Among which, licB is a choline transporter gene required for acquisition...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Choline
Share to Coinfection
Share to Haemophilus Infections

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Haemophilus influenzae

Share to Influenza A virus

Share to Orthomyxoviridae Infections

Share to Phosphorylcholine

Share to Transcription Factor CHOP

Source

Identifiers

PMID: 26521136
DOI: 10.1016/j.micpath.2015.10.010

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Haemophilus influenzae LicB contributes to lung damage in an aged mice co-infection model.PMID 26521136Read ↗

Genetic and functional analysis of the phosphorylcholine moiety of commensal Neisseria lipopolysaccharideSemantic proximity Read ↗

The position of phosphorylcholine on the lipopolysaccharide of Haemophilus influenzae affects binding and sensitivity to C-reactive protein-mediated killing.Semantic proximity Read ↗

The role of licA phase variation in the pathogenesis of invasive disease by Haemophilus influenzae type b.Semantic proximity Read ↗

<i>Klebsiella pneumoniae C</i> o-infection Leads to Fatal Pneumonia in SARS-CoV-2-infected MiceSemantic proximity Read ↗

Phosphorylcholine decoration of lipopolysaccharide differentiates commensal Neisseriae from pathogenic strains: identification of licA‐type genes in commensal NeisseriaeSemantic proximity Read ↗

Phosphorylcholine on the lipopolysaccharide of Haemophilus influenzae contributes to persistence in the respiratory tract and sensitivity to serum killing mediated by C-reactive protein.Semantic proximity Read ↗

Phosphorylcholine Allows for Evasion of Bactericidal Antibody by Haemophilus influenzaeSemantic proximity Read ↗

A C-terminal truncated mutation of licC attenuates the virulence of Streptococcus pneumoniae.Semantic proximity Read ↗

Repeated respiratory Mycoplasma pneumoniae infections in mice: effect of host genetic background.Semantic proximity Read ↗

The effect of mutations in genes required for lipopolysaccharide synthesis on Haemophilus influenzae type b colonization of human nasopharyngeal tissue.Semantic proximity Read ↗

The Haemophilus influenzae Sap transporter mediates bacterium-epithelial cell homeostasis.Semantic proximity Read ↗

Pneumococcal <i>licD2</i> gene is involved in phosphorylcholine metabolismSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.