Article
Decoding the non-coding genome: elucidating genetic risk outside the coding genome.
Genes, brain, and behavior - 1 Jan 2016
Barr C L, Misener V L
Abstract excerpt
Current evidence emerging from genome-wide association studies indicates that the genetic underpinnings of complex traits are likely attributable to genetic variation that changes gene expression, rather than (or in combination with) variation that changes protein-coding sequences. This is particularly compelling with respect to psychiatric disorders, as genetic changes in regulatory regions may result in...
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