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Article

Genes involved in the regulation of intestinal permeability and their role in ulcerative colitis.

Journal of digestive diseases - 1 Dec 2015

Prager Matthias, Buettner Janine, Buening Carsten

Abstract excerpt

OBJECTIVE: Genome-wide association studies have identified single nucleotide polymorphisms in genes that might influence intestinal barrier function (HNF4A, ECM1, CDH1 and LAMB1) to increase the risk for ulcerative colitis (UC). The aim of our study was to detect causative sequence alterations and provide a functional link to a disturbed intestinal permeability (IP) in UC. METHODS: A total of 19 UC patients with...

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Share to Colitis, Ulcerative
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26512799
DOI: 10.1111/1751-2980.12296

Genes

CDH1
ECM1
LAMB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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