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Article

Evaluation of the MLH1 I219V alteration in DNA mismatch repair activity and ulcerative colitis.

Inflammatory bowel diseases - 1 May 2008

Plotz Guido, Raedle Jochen, Spina Anna, Welsch Christoph, Stallmach Andreas, Zeuzem Stefan, Schmidt Carsten

Abstract excerpt

BACKGROUND: Inflammatory bowel diseases (IBDs; ulcerative colitis, UC, and Crohn's disease, CD) show familial clustering suggestive of a genetic background. A linkage susceptibility region for these diseases (IBD9) lies on chromosome 3p and includes the DNA mismatch repair gene MLH1. Loss of MLH1...

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Share to Adaptor Proteins, Signal Transducing
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18200512
DOI: 10.1002/ibd.20358

Genes

MLH1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18200512-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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