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Article

Influence of Matrix metalloproteinase 1 and 3 genetic variations on susceptibility and severity of juvenile idiopathic arthritis.

IUBMB life - 1 Dec 2015

Abd-Allah Somia H, El-Shal Amal S, Shalaby Sally M, Pasha Heba F, Abou El-Saoud Amany M, Abdel Galil Sahar M, Mahmoud Tysser A

Abstract excerpt

Juvenile idiopathic arthritis (JIA) is a chronic rheumatic disease affecting children aged less than 16 years, characterized by chronic synovitis, cartilage damage, and bony erosions mediated by matrix metalloproteinases (MMPs), mainly MMP-1 and MMP-3. The purpose of this study was to investigate MMP-1 and MMP-3 gene polymorphisms in patients with JIA, the role of genes in susceptibility to JIA, and their...

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Identifiers

PMID: 26510114
DOI: 10.1002/iub.1446

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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