Article
Brain Arousal Regulation in Carriers of Bipolar Disorder Risk Alleles.
Neuropsychobiology - 1 Jan 2015
Jawinski Philippe, Sander Christian, Mauche Nicole, Spada Janek, Huang Jue, Schmidt Anna, Häntzsch Madlen, Burkhardt Ralph, Scholz Markus, Hegerl Ulrich, Hensch Tilman
Abstract excerpt
OBJECTIVES: Recent genome-wide association studies identified a number of chromosomal risk loci for bipolar disorder (BD, 'manic-depressive illness'). According to the vigilance regulation model, the regulation of brain arousal (referred to as 'vigilance') when assessed via EEG is an emerging biomarker linked to the pathogenesis of manic and depressive episodes. On this basis, the present study aimed to assess...
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