Article
Scabrous overexpression in the eye affects R3/R4 cell fate specification and inhibits notch signaling.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Feb 2016
Muñoz-Soriano Verónica, Santos Diego, Durupt Fabrice C, Casani Sandra, Paricio Nuria
Abstract excerpt
BACKGROUND: Planar cell polarity (PCP) in the Drosophila eye is generated when immature ommatidial preclusters acquire opposite chirality in the dorsal and ventral halves of the eye imaginal disc and rotate 90 ° toward the equator. The scabrous (sca) gene is involved in R8 differentiation and in the correct spacing of ommatidial clusters in eye imaginal discs, but it was also suggested to be required during...
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