Article
Confrontation of scabrous expressing and non-expressing cells is essential for normal ommatidial spacing in the Drosophila eye.
Development (Cambridge, England) - 1 Jul 1994
Ellis M C, Weber U, Wiersdorff V, Mlodzik M
Abstract excerpt
The establishment of neural precursor cells in Drosophila depends on cell-cell interactions and lateral inhibition. Scabrous (sca) is involved in this process by preventing an excess of cells from adopting a neural precursor fate. Specifically in eye development, Sca protein function has been implicated in the spacing pattern that is essential for the ordered appearance of the ommatidial array. During this...
Topics
- Amino Acid Sequence
- Animals
- Chick Embryo
- Drosophila
- Embryonic Induction
- Eye
- Gene Expression
- Genes, Insect
- Humans
- Molecular Sequence Data
- Phenotype