Article
Drosophila eye development: Notch and Delta amplify a neurogenic pattern conferred on the morphogenetic furrow by scabrous.
Mechanisms of development - 1 Feb 1995
Baker N E, Zitron A E
Abstract excerpt
Loss of function mutations of scabrous and conditional alleles of Notch and Delta affect the pattern of morphogenetic furrow development. By studying differentiation of R8 cells, the first photoreceptor neuron subtype to differentiate, we show that all furrow cells pass through an R8-competent stage. Function of Notch and scabrous is necessary if most of these cells are to attain other cell fates. The scabrous...
Topics
- Animals
- Drosophila
- Drosophila Proteins
- Eye
- Gene Expression Regulation, Developmental
- Immunohistochemistry
- Insect Hormones
- Intracellular Signaling Peptides and Proteins
- Membrane Proteins
- Microscopy, Electron