Article
Identification of potential mutations and genomic alterations in the epithelial and spindle cell components of biphasic synovial sarcomas using a human exome SNP chip.
BMC medical genomics - 27 Oct 2015
Qi Yan, Wang Ning, Pang Li-Juan, Zou Hong, Hu Jian-Ming, Zhao Jin, Zhang Jun, Liu Chun-Xia, Zhang Wen-Jie, Yuan Xiang-Lin, Li Feng
Abstract excerpt
BACKGROUND: Synovial sarcoma (SS) is one of the most aggressive soft-tissue sarcomas and is noted for late local recurrence and metastasis. It is of uncertain histological origin and exhibits a biphasic histopathological form involving both the mesenchyme and epithelium. Thus, its diagnosis and therapy remain a huge challenge for clinicians and pathologists. This study aimed to determine whether differential...
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