Article
Association Between the Body Mass Index and Prostate Cancer at Biopsy is Modified by Genetic Risk: A Cross-Sectional Analysis in China.
Medicine - 1 Oct 2015
Zhang Gui-Ming, Zhu Yao, Chen Hai-Tao, Han Cheng-Tao, Liu Fang, Xu Jian-Feng, Ye Ding-Wei
Abstract excerpt
Herein, we aimed to examine whether the association of body mass index (BMI) with prostate cancer (PCa) at biopsy differs according to genetic susceptibility.In a multicenter prospective cohort including 1120 men undergoing diagnostic prostate biopsy in China, we evaluated the interaction between BMI and genetic risk score (GRS) comprising 24 PCa-associated single nucleotide polymorphisms (SNPs), as well as a GRS...
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