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Article

Reproducibility, performance, and clinical utility of a genetic risk prediction model for prostate cancer in Japanese.

PloS one - 1 Jan 2012

Akamatsu Shusuke, Takahashi Atsushi, Takata Ryo, Kubo Michiaki, Inoue Takahiro, Morizono Takashi, Tsunoda Tatsuhiko, Kamatani Naoyuki, Haiman Christopher A, Wan Peggy, Chen Gary K, Le Marchand Loic, Kolonel Laurence N, Henderson Brian E, Fujioka Tomoaki, Habuchi Tomonori, Nakamura Yusuke, Ogawa Osamu, Nakagawa Hidewaki

Abstract excerpt

Prostate specific antigen (PSA) is widely used as a diagnostic biomarker for prostate cancer (PC). However, due to its low predictive performance, many patients without PC suffer from the harms of unnecessary prostate needle biopsies. The present study aims to evaluate the reproducibility and performance of a genetic risk prediction model in Japanese and estimate its utility as a diagnostic biomarker in a...

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Identifiers

PMID: 23071574
DOI: 10.1371/journal.pone.0046454
PMCID: PMC3468627

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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