Article
The Cumulative Effect of Gene-Gene and Gene-Environment Interactions on the Risk of Prostate Cancer in Chinese Men.
International journal of environmental research and public health - 27 Jan 2016
Liu Ming, Shi Xiaohong, Yang Fan, Wang Jianye, Xu Yong, Wei Dong, Yang Kuo, Zhang Yaoguang, Wang Xin, Liang Siying, Chen Xin, Sun Liang, Zhu Xiaoquan, Zhao Chengxiao, Zhu Ling, Tang Lei, Zheng Chenguang, Yang Ze
Abstract excerpt
Prostate cancer (PCa) is a multifactorial disease involving complex genetic and environmental factors interactions. Gene-gene and gene-environment interactions associated with PCa in Chinese men are less studied. We explored the association between 36 SNPs and PCa in 574 subjects from northern China. Body mass index (BMI), smoking, and alcohol consumption were determined through self-administered questionnaires...
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