Article
The effects of height and BMI on prostate cancer incidence and mortality: a Mendelian randomization study in 20,848 cases and 20,214 controls from the PRACTICAL consortium.
Cancer causes & control : CCC - 1 Nov 2015
Davies Neil M, Gaunt Tom R, Lewis Sarah J, Holly Jeff, Donovan Jenny L, Hamdy Freddie C, Kemp John P, Eeles Rosalind, Easton Doug, Kote-Jarai Zsofia, Al Olama Ali Amin, Benlloch Sara, Muir Kenneth, Giles Graham G, Wiklund Fredrik, Gronberg Henrik, Haiman Christopher A, Schleutker Johanna, Nordestgaard Børge G, Travis Ruth C, Neal David, Pashayan Nora, Khaw Kay-Tee, Stanford Janet L, Blot William J, Thibodeau Stephen, Maier Christiane, Kibel Adam S, Cybulski Cezary, Cannon-Albright Lisa, Brenner Hermann, Park Jong, Kaneva Radka, Batra Jyotsna, Teixeira Manuel R, Pandha Hardev, Lathrop Mark, Smith George Davey, Martin Richard M
Abstract excerpt
BACKGROUND: Epidemiological studies suggest a potential role for obesity and determinants of adult stature in prostate cancer risk and mortality, but the relationships described in the literature are complex. To address uncertainty over the causal nature of previous observational findings, we investigated associations of height- and adiposity-related genetic variants with prostate cancer risk and mortality....
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