Article
The association between the IL-4, ADRβ2 and ADAM 33 gene polymorphisms and asthma in the Taiwanese population.
Journal of the Chinese Medical Association : JCMA - 1 Dec 2012
Chiang Chi-Huei, Lin Ming-Wei, Chung Ming-Yi, Yang Ueng-Cheng
Abstract excerpt
BACKGROUND: The association between genetic polymorphisms of ADRβ2, IL-4, and ADAM3 and asthma remains undetermined. Furthermore, it is not clear as to whether these three gene polymorphisms combined produce a correlative increase in asthmatic risk. METHODS: A total of 476 asthmatic patients and 115 healthy volunteers were enrolled. Single nucleotide polymorphisms (SNPs) of the C-589T IL-4 promoter (rs2243250),...
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