Article
Common variants in QPCT gene confer risk of schizophrenia in the Han Chinese population.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Mar 2016
Khan Raja Amjad Waheed, Chen Jianhua, Shen Jiawei, Li Zhiqiang, Wang Meng, Wen Zujia, Song Zhijian, Li Wenjin, Xu Yifeng, Shi Yongyong, Yi Qizhong, Ji Weidong
Abstract excerpt
Schizophrenia (SCZ) is a common and severe mental disorder, its etiology has not been elucidated completely. In one previous genome-wide association study (GWAS) of SCZ in the Caucasian population, the QPCT has been reported as susceptible gene for SCZ. The QPCT gene encodes Glutaminyl cyclase (QC), an enzyme which is involved in the post translational modification by converting N-terminal glutamate of protein to...
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