Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The TGM2 gene is associated with schizophrenia in a British population.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Apr 2009

Bradford Matilda, Law Matthew H, Stewart Andrew D, Shaw Duncan J, Megson Ian L, Wei Jun

Abstract excerpt

Several lines of evidence have suggested an interesting link between gluten ingestion and schizophrenia. Increased levels of gliadin antibodies have been observed in patients with schizophrenia. Tissue transglutaminase (transglutaminase 2, TGM2) is involved in the production of gliadin antibodies. To investigate genetic association of the TGM2 gene with schizophrenia, we detected eight single nucleotide...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to GTP-Binding Proteins
Share to Linkage Disequilibrium

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Nuclear Family

Share to Population Groups

Share to Protein Glutamine gamma Glutamyltransferase 2

Share to Schizophrenia

Share to Transglutaminases

Share to United Kingdom

Source

Identifiers

PMID: 18561261
DOI: 10.1002/ajmg.b.30813

Genes

TGM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The TGM2 gene is associated with schizophrenia in a British population.PMID 18561261Read ↗

The functional significance of the TGM2 gene in schizophrenia: a correlation of SNPs and circulating IL-2 levels.Semantic proximity Read ↗

Lack of genetic association of the TGM2 gene with schizophrenia in a Chinese population.Semantic proximity Read ↗

Support for association of HSPG2 with tardive dyskinesia in Caucasian populations.Semantic proximity Read ↗

Association of MCTP2 gene variants with schizophrenia in three independent samples of Scandinavian origin (SCOPE).Semantic proximity Read ↗

Immunoglobulin G genotypes and the risk of schizophrenia.Semantic proximity Read ↗

Missense mutations in theTGM2 gene encoding transglutaminase 2 are found in patients with early-onset type 2 diabetesSemantic proximity Read ↗

Association between ST8SIA2 and the Risk of Schizophrenia and Bipolar I Disorder across Diagnostic Boundaries.Semantic proximity Read ↗

Rare variant analysis in multiply affected families, association studies and functional analysis suggest a role for the ITGΒ4 gene in schizophrenia and bipolar disorder.Semantic proximity Read ↗

<i>MTHFR</i> C677T polymorphism and promoter methylation in schizophrenia patients with type 2 diabetes mellitus: evidence from a Han Chinese cohortSemantic proximity Read ↗

Identification of sialyltransferase 8B as a generalized susceptibility gene for psychotic and mood disorders on chromosome 15q25-26.Semantic proximity Read ↗

Association analysis of GRM2 and HTR2A with methamphetamine-induced psychosis and schizophrenia in the Japanese population.Semantic proximity Read ↗

Association of the HSPG2 gene with neuroleptic-induced tardive dyskinesia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.