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microRNAs Databases: Developmental Methodologies, Structural and Functional Annotations.

Interdisciplinary sciences, computational life sciences - 1 Sept 2017

Singh Nagendra Kumar

Abstract excerpt

microRNA (miRNA) is an endogenous and evolutionary conserved non-coding RNA, involved in post-transcriptional process as gene repressor and mRNA cleavage through RNA-induced silencing complex (RISC) formation. In RISC, miRNA binds in complementary base pair with targeted mRNA along with Argonaut proteins complex, causes gene repression or endonucleolytic cleavage of mRNAs and results in many diseases and...

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PMID: 27021491
DOI: 10.1007/s12539-016-0166-7

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