Article
The effect of SNPs on expression levels in Nimblegen RNA expression microarrays.
International journal of data mining and bioinformatics - 1 Jan 2015
Lund Sigrun Helga, Sigurdsson Asgeir, Gudjonsson Sigurjon Axel, Gudmundsson Julius, Gudbjartsson Daniel Fannar, Rafnar Thorunn, Stefansson Kari, Stefansson Gunnar
Abstract excerpt
In this paper the effect of SNPs on expression levels in Nimblegen RNA expression microarrays is investigated. A vast number of replicates of probe pairs representing both alleles of SNPs on 14 loci allows accurate estimation of the difference in signal intensities both within and between probe pairs. The majority of probe-pairs with sufficiently high expression have significant differences in expression levels...
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