Article
Genotyping and annotation of Affymetrix SNP arrays.
Nucleic acids research - 1 Jan 2006
Lamy Philippe, Andersen Claus L, Wikman Friedrik P, Wiuf Carsten
Abstract excerpt
In this paper we develop a new method for genotyping Affymetrix single nucleotide polymorphism (SNP) array. The method is based on (i) using multiple arrays at the same time to determine the genotypes and (ii) a model that relates intensities of individual SNPs to each other. The latter point allows us to annotate SNPs that have poor performance, either because of poor experimental conditions or because for one...
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