Article
Allele-specific expression analysis methods for high-density SNP microarray data.
Bioinformatics (Oxford, England) - 15 Apr 2012
Liu Ruijie, Maia Ana-Teresa, Russell Roslin, Caldas Carlos, Ponder Bruce A, Ritchie Matthew E
Abstract excerpt
MOTIVATION: In the past decade, a number of technologies to quantify allele-specific expression (ASE) in a genome-wide manner have become available to researchers. We investigate the application of single-nucleotide polymorphism (SNP) microarrays to this task, exploring data obtained from both cell lines and primary tissue for which both RNA and DNA profiles are available. RESULTS: We analyze data from two...
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