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Article

Hypermethylation of DLX4 predicts poor clinical outcome in patients with myelodysplastic syndrome.

Clinical chemistry and laboratory medicine - 1 May 2016

Zhang Ting-Juan, Zhou Jing-Dong, Yang Dong-Qin, Wang Yu-Xin, Yao Dong-Ming, Ma Ji-Chun, Wen Xiang-Mei, Guo Hong, Lin Jiang, Qian Jun

Abstract excerpt

BACKGROUND: Hypermethylation of DLX4 (distal-less homeobox 4) has been disclosed in a variety of cancers. Our work was aimed to examine the pattern of DLX4 methylation and further investigate its clinical relevance in patients with myelodysplastic syndrome (MDS). METHODS: Real-time quantitative methylation-specific PCR and bisulfite sequencing PCR were carried out to detect the level of DLX4 methylation. Clinical...

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Source

Identifiers

PMID: 26485746
DOI: 10.1515/cclm-2015-0536

Genes

DLX4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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