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Article

An integrative systems genetics approach reveals potential causal genes and pathways related to obesity.

Genome medicine - 20 Oct 2015

Kogelman Lisette J A, Zhernakova Daria V, Westra Harm-Jan, Cirera Susanna, Fredholm Merete, Franke Lude, Kadarmideen Haja N

Abstract excerpt

BACKGROUND: Obesity is a multi-factorial health problem in which genetic factors play an important role. Limited results have been obtained in single-gene studies using either genomic or transcriptomic data. RNA sequencing technology has shown its potential in gaining accurate knowledge about the transcriptome, and may reveal novel genes affecting complex diseases. Integration of genomic and transcriptomic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26482556
DOI: 10.1186/s13073-015-0229-0
PMCID: PMC4617184

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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