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Article

Genomic profile predicts the efficacy of neoadjuvant chemotherapy for cervical cancer patients.

BMC cancer - 19 Oct 2015

Horikawa Naoki, Baba Tsukasa, Matsumura Noriomi, Murakami Ryusuke, Abiko Kaoru, Hamanishi Junzo, Yamaguchi Ken, Koshiyama Masafumi, Yoshioka Yumiko, Konishi Ikuo

Abstract excerpt

BACKGROUND: Neoadjuvant chemotherapy (NAC) using platinum and irinotecan (CPT-11) followed by radical excision has been shown to be a valid treatment for locally advanced squamous cervical cancer (SCC) patients. However, in NAC-resistant or NAC-toxic cases, surgical treatment or radiotherapy might be delayed and the prognosis may be adversely affected. Therefore, it is important to establish a method to predict...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26482555
DOI: 10.1186/s12885-015-1703-1
PMCID: PMC4612400

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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