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Article

The impact of GGH -401C>T polymorphism on cisplatin-based chemoradiotherapy response and survival in cervical cancer.

Gene - 10 Jan 2013

Silva Inês Hilário, Nogueira-Silva Cristina, Figueiredo Tiago, Lombo Liliana, Faustino Ilda, Catarino Raquel, Nogueira Augusto, Pereira Deolinda, Medeiros Rui

Abstract excerpt

AIMS: Cervical cancer is the third most frequent cancer in women worldwide, mostly treated with cisplatin-based chemoradiotherapy. Since it is known that folate metabolism might interfere with cisplatin effectiveness, we intended to study the influence of the Gamma Glutamyl Hydrolase -401C>T polymorphism in treatment response in cervical cancer. METHODS: We retrospectively reviewed the clinical data of 167...

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Source

Identifiers

PMID: 23107767
DOI: 10.1016/j.gene.2012.10.038

Genes

GGH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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