Article
Association Between HIF-1 Alpha Gene Polymorphisms and Response in Patients Undergoing Neoadjuvant Chemotherapy for Locally Advanced Cervical Cancer.
Medical science monitor : international medical journal of experimental and clinical research - 5 Sept 2016
Chen Qing, Tian Wei-Jie, Huang Miao-Ling, Liu Chang-Hao, Yao Ting-Ting, Guan Mei-Mei
Abstract excerpt
BACKGROUND The aim of the study was to assess whether HIF-1α polymorphisms have an effect on the response to chemotherapy of locally advanced cervical cancer (LACC) patients treated with platinum-based neoadjuvant chemotherapy (NACT) and radical surgery. MATERIAL AND METHODS We conducted a retrospective study in 162 LACC patients. Hypoxia-inducible factor 1α C1772T and G1790A genetic polymorphisms were...
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