Article
XRCC1 Arginine194Tryptophan and GGH-401Cytosine/Thymine polymorphisms are associated with response to platinum-based neoadjuvant chemotherapy in cervical cancer.
Gynecologic oncology - 1 Dec 2008
Kim Kidong, Kang Soon-Beom, Chung Hyun Hoon, Kim Jae Weon, Park Noh-Hyun, Song Yong-Sang
Abstract excerpt
OBJECTIVE: The objective of this study was to evaluate the association of single nucleotide polymorphisms (SNPs) of genes which are involved in DNA synthesis and repair with the response to platinum-based neoadjuvant chemotherapy (NAC) and disease-free survival (DFS) in patients with cervical cancer who were treated with NAC followed by radical hysterectomy. METHODS: A retrospective review was performed on 66...
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