Article
The effects of a muscarinic receptor 1 gene variant on cortical thickness and surface area in schizophrenia.
Psychiatry research. Neuroimaging - 30 Oct 2018
Carruthers Sean P, Gurvich Caroline T, Cropley Vanessa L, Pantelis Christos, Bousman Chad, Lenroot Rhoshel K, Bruggemann Jason M, Weickert Thomas, Rossell Susan L
Abstract excerpt
Individuals with schizophrenia who are homozygous at the c.267C>A single nucleotide polymorphism (rs2067477) within the cholinergic muscarinic M1 receptor gene have been reported to perform less well on the Wisconsin Card Sorting Test and demonstrate reduced grey matter volume in the right precentral gyrus. We investigated if rs2067477 genotype variation influenced cortical thickness and cortical surface area in...
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