Article
A 1-bp deletion in Fgf5 causes male-dominant long hair in the Syrian hamster.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Dec 2015
Yoshizawa Yasuhiro, Wada Kenta, Shimoi Gaku, Shiomi Gaku, Kameyama Yuichi, Wakabayashi Yuichi, Fukuta Katsuhiro, Hashizume Ryoichi
Abstract excerpt
Hair length in mammals is generally regulated by the hair cycle, and its disruption leads to abnormal hair morphogenesis in several species. FGF5, one of the hair cycle regulators, has a role in inducing catagen, and that mutation causes abnormal hair length in both sexes in humans, mice, dogs, and cats. Male-dominant long-haired coat (MALC) is an inbred strain of Syrian hamster exhibiting spontaneous long hair...
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