Article
Four independent mutations in the feline fibroblast growth factor 5 gene determine the long-haired phenotype in domestic cats.
The Journal of heredity - 1 Jan 2000
Kehler James S, David Victor A, Schäffer Alejandro A, Bajema Kristina, Eizirik Eduardo, Ryugo David K, Hannah Steven S, O'Brien Stephen J, Menotti-Raymond Marilyn
Abstract excerpt
To determine the genetic regulation of "hair length" in the domestic cat, a whole-genome scan was performed in a multigenerational pedigree in which the "long-haired" phenotype was segregating. The 2 markers that demonstrated the greatest linkage to the long-haired trait (log of the odds > or = 6) flanked an estimated 10-Mb region on cat chromosome B1 containing the Fibroblast Growth Factor 5 (FGF5) gene, a...
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