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Article

A computational chemistry perspective on the current status and future direction of hepatitis B antiviral drug discovery.

Antiviral research - 1 Nov 2015

Morgnanesi Dante, Heinrichs Eric J, Mele Anthony R, Wilkinson Sean, Zhou Suzanne, Kulp John L

Abstract excerpt

Computational chemical biology, applied to research on hepatitis B virus (HBV), has two major branches: bioinformatics (statistical models) and first-principle methods (molecular physics). While bioinformatics focuses on statistical tools and biological databases, molecular physics uses mathematics and chemical theory to study the interactions of biomolecules. Three computational techniques most commonly used in...

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Identifiers

PMID: 26477294
DOI: 10.1016/j.antiviral.2015.10.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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