Article
Using structural analysis to explore the role of hepatitis B virus mutations in immune escape from liver cancer in Chinese, European and American populations.
Journal of biomolecular structure & dynamics - 1 Mar 2022
Gu Shuanglin, Lv Li, Lin Xue, Li Xingyu, Dai Juncheng, Zhang Jianqiong, Kong Ren, Xie Wei, Li Jian
Abstract excerpt
Hepatitis B virus (HBV) infection is an important problem threatening human health. After HBV virus invades human body, it may assemble a complete virus particle in the cytoplasm to trigger the immune reaction, especially the interaction between the HBV virus and the host that mediated by CD8+ T cell. We collected the sequences of HBV from the HBVdb database, then screened candidate mutation sites in Chinese,...
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