Article
Absence of association between major vault protein (MVP) gene polymorphisms and drug resistance in Chinese Han patients with partial epilepsy.
Journal of the neurological sciences - 15 Nov 2015
Zhou Luo, Zhang Mengqi, Long Hongyu, Long Lili, Xie Yuanyuan, Liu Zhaoqian, Kang Jin, Chen Qihua, Feng Li, Xiao Bo
Abstract excerpt
Drug resistance in epilepsy is common despite many antiepileptic drugs (AEDs) available for treatment. The development of drug resistant epilepsy may be a result of multiple factors. Several previous studies reported that the major vault protein (MVP) was significantly increased in epileptogenic brain tissues resected from patients with partial-onset seizures, indicating the possible involvement of MVP in drug...
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