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Article

Major vault protein, a marker of drug resistance, is upregulated in refractory epilepsy.

Epilepsia - 1 Nov 2003

Sisodiya Sanjay M, Martinian Lillian, Scheffer George L, van der Valk Paul, Cross J Helen, Scheper Rik J, Harding Brian N, Thom Maria

Abstract excerpt

PURPOSE: The molecular basis of drug resistance in epilepsy is being explored. Two proteins associated with drug resistance in cancer, P-glycoprotein and multidrug resistance-associated protein 1, are upregulated in human epileptogenic pathologies. Other proteins associated with resistance in can...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 14636345
DOI: 10.1046/j.1528-1157.2003.21803.x

Genes

MVP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14636345-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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