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Article

EGFR mutations in non-small-cell lung cancer among smokers and non-smokers: a meta-analysis.

Environmental and molecular mutagenesis - 1 Jan 2012

Ren Jing-Hua, He Wen-Shan, Yan Guo-Li, Jin Min, Yang Kun-Yu, Wu Gang

Abstract excerpt

Mounting evidence has suggested somatic mutations in the EGFR gene are associated with better responsiveness to EGFR tyrosine kinase inhibitors (TKIs) in patients with non-small-cell lung cancer (NSCLC). Some, but not all, studies have reported that the mutations were more frequently observed in patients without a smoking history. To comprehensively address this issue, we performed a meta-analysis to evaluate the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22223435
DOI: 10.1002/em.20680

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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