Article
Identification of Prognostic and Susceptibility Markers in Chronic Myeloid Leukemia Using Next Generation Sequencing.
Ethiopian journal of health sciences - 1 Mar 2018
Shokeen Yogender, Sharma Neeta Raj, Vats Abhishek, Taneja Vibha, Minhas Sachin, Jauhri Mayank, Sankaran Satish, Aggarwal Shyam
Abstract excerpt
BACKGROUND: Incidence of Chronic Myeloid Leukemia (CML) is continuously increasing and expected to reach 100,000 patients every year by 2030. Though the discovery of Imatinib Mesylate (IM) has brought a paradigm shift in CML treatment, 20% patients show resistance to this tyrosine kinase inhibiter (TKI). Therefore, it is important to identify markers, which can predict the occurrence and prognosis of CML....
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