Article
A combinatorial radiographic phenotype may stratify patient survival and be associated with invasion and proliferation characteristics in glioblastoma.
Journal of neurosurgery - 1 Apr 2016
Rao Arvind, Rao Ganesh, Gutman David A, Flanders Adam E, Hwang Scott N, Rubin Daniel L, Colen Rivka R, Zinn Pascal O, Jain Rajan, Wintermark Max, Kirby Justin S, Jaffe C Carl, Freymann John
Abstract excerpt
OBJECTIVE: Individual MRI characteristics (e.g., volume) are routinely used to identify survival-associated phenotypes for glioblastoma (GBM). This study investigated whether combinations of MRI features can also stratify survival. Furthermore, the molecular differences between phenotype-induced groups were investigated. METHODS: Ninety-two patients with imaging, molecular, and survival data from the TCGA (The...
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