Article
Imaging-genomics reveals driving pathways of MRI derived volumetric tumor phenotype features in Glioblastoma.
BMC cancer - 8 Aug 2016
Grossmann Patrick, Gutman David A, Dunn William D, Holder Chad A, Aerts Hugo J W L
Abstract excerpt
BACKGROUND: Glioblastoma (GBM) tumors exhibit strong phenotypic differences that can be quantified using magnetic resonance imaging (MRI), but the underlying biological drivers of these imaging phenotypes remain largely unknown. An Imaging-Genomics analysis was performed to reveal the mechanistic associations between MRI derived quantitative volumetric tumor phenotype features and molecular pathways. METHODS: One...
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