Article
Radiogenomic-Based Survival Risk Stratification of Tumor Habitat on Gd-T1w MRI Is Associated with Biological Processes in Glioblastoma.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Apr 2020
Beig Niha, Bera Kaustav, Prasanna Prateek, Antunes Jacob, Correa Ramon, Singh Salendra, Saeed Bamashmos Anas, Ismail Marwa, Braman Nathaniel, Verma Ruchika, Hill Virginia B, Statsevych Volodymyr, Ahluwalia Manmeet S, Varadan Vinay, Madabhushi Anant, Tiwari Pallavi
Abstract excerpt
PURPOSE: To (i) create a survival risk score using radiomic features from the tumor habitat on routine MRI to predict progression-free survival (PFS) in glioblastoma and (ii) obtain a biological basis for these prognostic radiomic features, by studying their radiogenomic associations with molecular signaling pathways. EXPERIMENTAL DESIGN: Two hundred three patients with pretreatment Gd-T1w, T2w, T2w-FLAIR MRI...
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