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Extensive In Silico Analysis of <i>ATL1</i> Gene: Discovered Five Mutations that may Cause Hereditary Spastic Paraplegia Type 3A

2019-10-25

Abstract excerpt

<h4>ABSTRACT</h4> <h4>BACKGROUND</h4> Hereditary spastic paraplegia type 3A (SPG3A) is a neurodegenerative disease inherited type of Hereditary spastic paraplegia (HSP). It is the second most frequent type of HSP; which Characterized by muscle stiffness with paraplegia and early-onset of symptoms. This is the first translational bioinformatics analysis in a coding region of ATL1 gene which aims to categorize ns...

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Literature Corpus work: f103a638-d6e9-5abf-a477-76b000b77102
DOI: 10.1101/818302

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